| Revenues | — | — | — |
| License and milestone revenues | 15a | 3.5a | 1a |
| Collaboration revenues | 3.47a | 4.03a | 6.59a |
| Realization of revenue participation right purchase agreement | 0a | 0a | 87a |
| Total revenues | 18.47a | 7.53a | 94.59a |
| Operating expenses | — | — | — |
| Research and development | -339.41a | -330.12a | -240.81a |
| General and administrative | -215.31a | -173.61a | -177.98a |
| Total operating expenses | -554.72a | -503.74a | -418.79a |
| Operating loss | -536.25a | -496.21a | -324.2a |
| Interest expense | -37.7a | -28.31a | -19.41a |
| Loss on extinguishment of debt | 0a | 0a | -24.94a |
| Non-cash interest expense on liabilities related to revenue participation right purchase agreements | -48.81a | -29.36a | -31.74a |
| Interest and other income, net | 51.53a | 27.63a | 11.34a |
| Change in fair value of derivative liabilities | 1.3a | 0a | 0a |
| Change in fair value of liabilities related to RPI transactions | -19.6a | 0a | 0a |
| Net loss | -589.53a | -526.24a | -388.96a |