| Revenues | — | — | — |
| Net product sales | 2,330.6a | 1,860.6a | 1,440.9a |
| Collaboration revenue | 24.7a | 26.5a | 47.8a |
| Total revenues | 2,355.3a | 1,887.1a | 1,488.7a |
| Operating expenses | — | — | — |
| Cost of revenues | -34a | -39.7a | -23.2a |
| Research and development | -731.1a | -565a | -463.8a |
| Acquired in-process research and development | -12.5a | -143.9a | |
| Selling, general, and administrative | -1,007.2a | -887.6a | -752.7a |
| Total operating expenses | -1,784.8a | -1,636.2a | -1,239.7a |
| Operating income | 570.5a | 250.9a | 249a |
| Other (expense) income | — | — | — |
| Unrealized (loss) gain on equity investments | -37.1a | 28.4a | 30.8a |
| Charges associated with convertible senior notes | -138.4a | | -70a |
| Interest income and other, net | 91a | 52.8a | 4.1a |
| Total other (expense) income, net | -84.5a | 81.2a | -35.1a |
| Income before provision for income taxes | 486a | 332.1a | 213.9a |
| Provision for income taxes | -144.7a | -82.4a | -59.4a |
| Net income | 341.3a | 249.7a | 154.5a |