| Revenues | — | — | — |
| Product sales, net | 1,083,534a | 919,998a | 777,552a |
| Manufacturing and royalty revenues | 474,095a | 743,388a | 331,983a |
| License revenue | 0a | 0a | 2,000a |
| Research and development revenue | 3a | 19a | 260a |
| Total revenues | 1,557,632a | 1,663,405a | 1,111,795a |
| Expenses | — | — | — |
| Cost of goods manufactured and sold (exclusive of amortization of acquired intangible assets shown below) | -245,331a | -253,037a | -218,068a |
| Research and development | -245,326a | -270,806a | -272,702a |
| Selling, general and administrative | -645,238a | -689,751a | -590,751a |
| Amortization of acquired intangible assets | -1,101a | -35,689a | -36,363a |
| Total expenses | -1,136,996a | -1,249,283a | -1,117,884a |
| Operating income from continuing operations | 420,636a | 414,122a | -6,089a |
| Other income (expense), net | — | — | — |
| Interest income | 42,450a | 30,854a | 7,629a |
| Interest expense | -22,578a | -23,032a | -13,040a |
| Change in the fair value of contingent consideration | 0a | 0a | -21,750a |
| Other income (expense), net | 3,242a | -425a | 2,122a |
| Total other income (expense), net | 23,114a | 7,397a | -25,039a |
| Income (loss) before income taxes | 443,750a | 421,519a | -31,128a |
| Income tax provision (benefit) | 71,612a | -97,638a | 2,024a |
| Net income (loss) from continuing operations | 372,138a | 519,157a | -33,152a |
| Loss from discontinued operations, net of tax | -5,068a | -163,400a | -125,115a |
| Net income (loss) | 367,070a | 355,757a | -158,267a |