| Assets | — | — |
| Current assets | — | — |
| Cash and cash equivalents | 102.01a | 71.29a |
| Marketable securities | 513.47a | 639.36a |
| Accounts receivable | 75.8a | 42.83a |
| Unbilled accounts receivable | 1.81a | 0.35a |
| Inventory | 13.61a | 21.22a |
| Prepaid expenses and other current assets | 35.97a | 33.35a |
| Total current assets | 742.68a | 808.39a |
| Marketable securities | 248.45a | 56.53a |
| Property and equipment, net | 36.59a | 41.96a |
| Operating lease right-of-use assets, net | 64.18a | 73.69a |
| Restricted cash | 11.63a | 10.24a |
| Equity investment | 28.7a | 27.79a |
| Other assets | 47.59a | 30.65a |
| Total assets | 1,179.81a | 1,049.25a |
| Liabilities and stockholders’ equity | — | — |
| Current liabilities | — | — |
| Accounts payable | 6.79a | 4.71a |
| Accrued expenses | 133.09a | 127.99a |
| Current portion of operating lease liabilities | 13.35a | 11.93a |
| Current portion of deferred revenue | 2.01a | 0.81a |
| Current portion of liabilities related to the sale of future royalties and revenues | 61.65a | 39.2a |
| Current portion of term loan | 43.92a | 30.28a |
| Total current liabilities | 260.8a | 214.92a |
| Operating lease liabilities, net of current portion | 68.79a | 81.75a |
| Deferred revenue, net of current portion | 8.19a | 4.79a |
| Liabilities related to the sale of future royalties and revenues, net of current portion | 193.52a | 402.43a |
| Term loan, net of current portion | 343.05a | 208.54a |
| Other long-term liabilities | 6.79a | 6.21a |
| Total liabilities | 881.15a | 918.64a |
| Stockholders’ equity | — | — |
| Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued and outstanding | 0a | 0a |
| Common stock, $0.001 par value; 120,000,000 shares authorized; 63,712,256 and 61,147,236 shares issued and outstanding at December 31, 2024 and December 31, 2023, respectively | 0.06a | 0.06a |
| Additional paid-in capital | 2,709.18a | 2,473.99a |
| Accumulated other comprehensive loss | -3.55a | -3.5a |
| Accumulated deficit | -2,407.03a | -2,339.94a |
| Total stockholders’ equity | 298.67a | 130.61a |
| Total liabilities and stockholders’ equity | 1,179.81a | 1,049.25a |